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Article

Role of EGF Receptor Regulatory Networks in the Host Response to Viral Infections

10 Jan 2022

Abstract excerpt

In this review article, we will first provide a brief overview of EGF receptor (EGFR) structure and function, and its importance as a therapeutic target in epithelial carcinomas. We will then compare what is currently known about canonical EGFR trafficking pathways that are triggered by ligand binding, versus ligand-independent pathways activated by a variety of intrinsic and environmentally induced cellular...

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Identifiers

PMID: 35083168
DOI: 10.3389/fcimb.2021.820355

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