Article
Oncogenic genes and human malignancy.
The Yale journal of biology and medicine - 1 Jan 2000
Lebowitz P
Abstract excerpt
All vertebrates possess a series of genes which are homologs of the oncogenic genes of acute transforming retroviruses. Two lines of evidence suggest that these genes may play a role in the development of human malignancy: (1) DNA from a variety of human tumors transforms NIH 3T3 mouse fibroblast...
Topics
- Animals
- Cell Transformation, Neoplastic
- Chromosome Mapping
- Genes, Viral
- Humans
- Karyotyping
- Mutation
- Neoplasms
- Oncogenes
- Transformation, Genetic
- Tumor Virus Infections