Biochemistry and molecular biology of the human CYP2C subfamily.

doi:10.1097/00008571-199412000-00001

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Article

Biochemistry and molecular biology of the human CYP2C subfamily.

Pharmacogenetics - 1 Dec 1994

Goldstein J A, de Morais S M

Abstract excerpt

The cytochromes P450 (CYP) are a superfamily of hemoproteins which metabolize foreign chemicals as well as a number of endogenous compounds such as steroids. The human CYP2C subfamily appears to principally metabolize a number of clinically used drugs. Four members of this subfamily have been identified in humans: CYP2C8, CYP2C9, CYP2C18, and CYP2C19. CYP2C9 is important in the metabolism certain of...

Topics

Amino Acid Sequence
Aryl Hydrocarbon Hydroxylases
Base Sequence
Cloning, Molecular
Cytochrome P-450 CYP2C19
Cytochrome P-450 Enzyme System
DNA, Complementary
Humans
In Vitro Techniques
Liver
Mixed Function Oxygenases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Biology

Molecular Sequence Data

Multigene Family

Mutation

Polymorphism, Genetic

RNA Splicing

Recombinant Proteins

Source

Open in PubMed

Identifiers

PMID: 7704034
DOI: 10.1097/00008571-199412000-00001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7704034-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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