Article
Biochemistry and molecular biology of the human CYP2C subfamily.
Pharmacogenetics - 1 Dec 1994
Goldstein J A, de Morais S M
Abstract excerpt
The cytochromes P450 (CYP) are a superfamily of hemoproteins which metabolize foreign chemicals as well as a number of endogenous compounds such as steroids. The human CYP2C subfamily appears to principally metabolize a number of clinically used drugs. Four members of this subfamily have been identified in humans: CYP2C8, CYP2C9, CYP2C18, and CYP2C19. CYP2C9 is important in the metabolism certain of...
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