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Article

Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes.

The Journal of allergy and clinical immunology - 1 Jul 2006

Barnes Kathleen C, Grant Audrey, Gao Peisong, Baltadjieva Daniela, Berg Tiina, Chi Peter, Zhang Shu, Zambelli-Weiner April, Ehrlich Eva, Zardkoohi Omeed, Brummet Mary E, Stockton Maria, Watkins Tonya, Gao Li, Gittens Marquita, Wills-Karp Marsha, Cheadle Christopher, Beck Lisa A, Beaty Terri H, Becker Kevin G, Garcia Joe G N, Mathias Rasika A

Abstract excerpt

BACKGROUND: The gene encoding acyloxyacyl hydroxylase (AOAH), an enzyme that hydrolyzes secondary fatty acyl chains of LPS, is localized on chromosome 7p14-p12, where evidence for linkage to total IgE (tIgE) concentrations and asthma has been previously reported. OBJECTIVE: We hypothesized that variants in AOAH are associated with asthma and related phenotypes. Because both AOAH and soluble CD14 respond to LPS,...

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Source

Identifiers

PMID: 16815140
DOI: 10.1016/j.jaci.2006.03.036

Genes

AOAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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