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Article

Evaluation of the CD14/-260 polymorphism and house dust endotoxin exposure in the Barbados Asthma Genetics Study.

The Journal of allergy and clinical immunology - 1 Jun 2005

Zambelli-Weiner April, Ehrlich Eva, Stockton Maria L, Grant Audrey V, Zhang Shu, Levett Paul N, Beaty Terri H, Barnes Kathleen C

Abstract excerpt

BACKGROUND: Both a functional promoter polymorphism in the gene encoding CD14 (C-260T) and exposure to endotoxin are believed to play key roles in modulating the immune response and expression of atopic disease. OBJECTIVE: We aimed to evaluate the role of the CD14 C-260T polymorphism in a population of African descent and to test for interaction between this genotype and house dust endotoxin (HDE) exposure on...

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Source

Identifiers

PMID: 15940135
DOI: 10.1016/j.jaci.2005.03.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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