Article
A novel locus for dilated cardiomyopathy, diffuse myocardial fibrosis, and sudden death on chromosome 10q25-26.
Journal of the American College of Cardiology - 4 Jul 2006
Ellinor Patrick T, Sasse-Klaassen Sabine, Probst Susanne, Gerull Brenda, Shin Jordan T, Toeppel Andrea, Heuser Arnd, Michely Beate, Yoerger Danita M, Song Bong-Seok, Pilz Bernhard, Krings Gregor, Coplin Bruce, Lange Peter E, Dec G William, Hennies Hans Christian, Thierfelder Ludwig, MacRae Calum A
Abstract excerpt
OBJECTIVES: We sought to identify the genetic locus for an inherited form of dilated cardiomyopathy (DCM) that is characterized by diffuse myocardial fibrosis and sudden death. BACKGROUND: Genetic studies have mapped multiple loci for DCM, which is a major cause of nonischemic heart failure; howe...
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