Article
A novel locus for dilated cardiomyopathy maps to canine chromosome 8.
Genomics - 1 Jun 2008
Werner Petra, Raducha Michael G, Prociuk Ulana, Sleeper Meg M, Van Winkle Thomas J, Henthorn Paula S
Abstract excerpt
Dilated cardiomyopathy (DCM), the most common form of cardiomyopathy, often leads to heart failure and sudden death. While a substantial proportion of DCMs are inherited, mutations responsible for the majority of DCMs remain unidentified. A genome-wide linkage study was performed to identify the locus responsible for an autosomal recessive inherited form of juvenile DCM (JDCM) in Portuguese water dogs using 16...
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