Article
Genetic association mapping under founder heterogeneity via weighted haplotype similarity analysis in candidate genes.
Genetic epidemiology - 1 Nov 2004
Yu K, Gu C Charles, Province M, Xiong C J, Rao D C
Abstract excerpt
Taking advantage of increasingly available high-density single nucleotide polymorphism (SNP) markers within genes and across genomes, more and more genetic association studies began to use multiple closely linked markers in candidate genes. A practical analytical challenge arising in such studies is the possibility that not all case chromosomes have inherited disease-causing mutations from a common ancestral...
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