Article
Kank proteins: structure, functions and diseases.
Cellular and molecular life sciences : CMLS - 1 Aug 2009
Kakinuma N, Zhu Y, Wang Y, Roy B C, Kiyama R
Abstract excerpt
The Kank family of proteins, Kank1-Kank4, are characterized by their unique structure, coiled-coil motifs in the N-terminal region, and ankyrin-repeats in the C-terminal region, with an additional motif, the KN motif, at the N-terminus. Kank1 was obtained by positional cloning of a tumor suppressor gene in renal cell carcinoma, while the other members were found by homology search. The family is involved in the...
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