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Article

Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Jun 2006

Pratt Thomas, Conway Christopher D, Tian Natasha M M-L, Price David J, Mason John O

Abstract excerpt

Retinal ganglion cell (RGC) axons from each eye execute a series of maneuvers as they converge on the ventral surface of the brain at the optic chiasm for sorting into the optic tracts. Heparan sulfate proteoglycans (HSPGs) are extracellular glycoproteins involved in cell-surface interactions. HSPGs exhibit massive structural diversity, conferred partly by extensive post-translational modification including...

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Identifiers

PMID: 16807321
DOI: 10.1523/JNEUROSCI.0505-06.2006
PMCID: PMC6673919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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