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Article

Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance.

Current biology : CB - 23 Mar 2004

Johnson Karl G, Ghose Aurnab, Epstein Elizabeth, Lincecum John, O'Connor Michael B, Van Vactor David

Abstract excerpt

The presentation of secreted axon guidance factors plays a major role in shaping central nervous system (CNS) connectivity. Recent work suggests that heparan sulfate (HS) regulates guidance factor activity; however, the in vivo axon guidance roles of its carrier proteins (heparan sulfate proteogl...

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Identifiers

PMID: 15043815
DOI: 10.1016/j.cub.2004.02.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15043815-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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