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Article

Early temporal-specific responses and differential sensitivity to lithium and Wnt-3A exposure during heart development.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2006

Manisastry Shyam M, Han Mingda, Linask Kersti K

Abstract excerpt

Members of both Wnt and bone morphogenetic protein (BMP) families of signaling molecules are important in heart development. We previously demonstrated that beta-catenin, a key downstream intermediary of the canonical Wnt signaling pathway, delineates the dorsal boundary of the cardiac compartments in an anteroposterior progression. We hypothesized the progression involves canonical Wnt signaling and reflects...

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PMID: 16804895
DOI: 10.1002/dvdy.20878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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