Association of type 1 diabetes mellitus with the HLA-DQA1*0301 allele in a Tunisian population.

doi:10.1016/0923-2494(91)90060-v

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Article

Association of type 1 diabetes mellitus with the HLA-DQA1*0301 allele in a Tunisian population.

Research in immunology - 1 Jan 2000

Bardi R, Ju L Y, Jenhani S, Ayed K, Chammakhi S, Charron D

Abstract excerpt

HLA class II antigens are transmembrane glycosylated heterodimers composed of an alpha and a beta chain. Several of these chains are highly polymorphic. The structural bases of the polymorphism are nucleotide acid substitutions which are situated in the first domain (exon II) of alpha and beta ge...

Topics

Alleles
Base Sequence
DNA
Diabetes Mellitus, Type 1
Gene Frequency
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DR Antigens
Humans
Molecular Sequence Data
Polymorphism, Restriction Fragment Length
Tunisia

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