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Article

Extended HLA haplotypes in multiplex families with insulin dependent diabetes mellitus in Tunisian population: HLA serological typing and RFLP analysis.

Disease markers - 1 Jan 2000

Jenhani F, Bardi R, Ayed K, Chammakhi S, Jeddi M, Labonne M P, Gebuhrer L, Betuel H

Abstract excerpt

Haplotypes including HLA A, B, C, DR, and DQ were compared in a study population comprising 18 Tunisian multiplex families with diabetic children. Eighty haplotypes found in IDDM patients were compared with 148 haplotypes present in healthy family members. RFLP analysis showed that two DR subtype...

Topics

Diabetes Mellitus, Type 1
Gene Frequency
Genetic Predisposition to Disease
HLA Antigens
HLA-DQ Antigens
Haplotypes
Polymorphism, Restriction Fragment Length
Tunisia

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1983195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1983195-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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