Article
Association of HLA-DR-DQ polymorphisms with diabetes in Tunisian patients.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis - 1 Oct 2013
Fekih Mrissa Najiba, Mrad Meriem, Ouertani Haroun, Baatour Makrem, Sayeh Aycha, Nsiri Brahim, Lamine Khaled, Zidi Borni, Gritli Nasreddine
Abstract excerpt
OBJECTIVE: Type 1 diabetes (T1D) is a polygenic disease whose principal locus is the human leukocytes antigen (HLA) region. The aim of this study was to evaluate HLA DR-DQ alleles and to asses them as risk factors for type 1 diabetes in the Tunisian population. MATERIALS AND METHODS: A total of 119 subjects with diabetes were tested for HLA class II alleles and compared with 292 healthy controls. HLA DRB1 and...
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