Article
Association of HLA-DRB1 and -DQ Alleles and Haplotypes with Type 1 Diabetes in Jordanians.
Endocrine, metabolic & immune disorders drug targets - 1 Jan 2020
Khdair Sawsan I, Jarrar Wassan, Jarrar Yazun Bashir, Bataineh Safa'a, Al-Khaldi Omar
Abstract excerpt
BACKGROUND: The Human Leukocyte Antigen (HLA) class II genes, particularly the HLADR and -DQ loci, have been shown to play a crucial role in Type 1 Diabetes (T1D) development. OBJECTIVE: This study is the first to examine the contribution of the HLA-DR/DQ alleles and haplotypes to T1D susceptibility in Jordanians. METHODS: Polymerase chain reaction sequence-specific primers (PCR-SSP) were used to genotype 41...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
