Article
[Variant fusion transcript in ALL children with E2A-PBX1 fusion gene positive].
Zhongguo shi yan xue ye xue za zhi - 1 Jun 2006
Li Zhi-Gang, Zhao Wei, Wu Min-Yuan, Hu Ya-Mei
Abstract excerpt
The study was aimed to investigate the expression of E2A-PBX1 fusion gene in children with acute lymphoblastic leukemia (ALL). The primers located at different sites of E2A and PBX1 gene were used to screen for the fusion gene in 410 children with ALL, including 362 cases of B cell ALL and 48 cases of T cell ALL. The results showed that 17 children carried the fusion gene. The positive rate was 4.1%. Furthermore,...
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