Article
Detection of E2A-PBX1 fusion transcripts in human non-small-cell lung cancer.
Journal of experimental & clinical cancer research : CR - 20 May 2013
Mo Min-Li, Chen Zhao, Zhou Hai-Meng, Li Hui, Hirata Tomomi, Jablons David M, He Biao
Abstract excerpt
BACKGROUND: E2A-PBX1 fusion gene caused by t(1;19)(q23;p13), has been well characterized in acute lymphoid leukemia (ALL). There is no report on E2A-PBX1 fusion transcripts in non-small-cell lung cancer (NSCLC). METHODS: We used polymerase chain reaction (PCR) to detect E2A-PBX1 fusion transcripts in human NSCLC tissue specimens and cell lines. We analyzed correlation of E2A-PBX1 fusion transcripts with clinical...
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