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Article

Carrier detection and prenatal diagnosis in 98 families of haemophilia A by linkage analysis and direct detection of mutations.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 1991

Lavergne J M, Laurian Y, Dudilleux A, Larrieu M J, Bahnak B R, Meyer D

Abstract excerpt

489 individuals from 98 families with a haemophilia A member were studied with restriction fragment length polymorphisms (RFLPs) for carrier detection and prenatal diagnosis. Five intragenic polymorphisms revealed with the restriction enzymes BclI, XbaI, BglI, HindIII and AlwNI and one extragenic multiallelic polymorphism (St14) at the DXS52 locus were used. The combination of the five intragenic polymorphisms...

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Source

Identifiers

PMID: 1680009
DOI: 10.1097/00001721-199104000-00012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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