Article
Genomic diagnosis of haemophilia A and B in the German Democratic Republic.
Folia haematologica (Leipzig, Germany : 1928) - 1 Jan 1990
Herrmann F H, Wehnert M, Schröder W
Abstract excerpt
Since 1986 the genomic diagnosis of haemophilia A and B in the GDR is realized as a national programme. Until Aug. 1989 56 families at risk of haemophilia A are analysed using RFLPs of different intragenic and intergenic probes (BclI/F8e 16-19, KpnI-XbaI/int 22, TaqI/St 14.1). 117 out of 162 females at risk being heterozygous were identified as carriers, in 40 cases the carrier state was excluded, and in 5...
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