Article
Carrier detection and prenatal diagnosis of hemophilia in developing countries.
Seminars in thrombosis and hemostasis - 1 Nov 2005
Peyvandi Flora
Abstract excerpt
Hemophilia A and B, inherited as X-linked recessive traits, are the most common hereditary hemorrhagic disorders caused by a deficiency or dysfunction of coagulation factor VIII (FVIII) or FIX, respectively. Hemophilia is prevalent worldwide, without ethnic or geographic limitations, and remains a life-threatening and often disabling condition. Advances in molecular medicine in this century have markedly improved...
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