Article
A highly informative, multiplexed assay for the indirect detection of hemophilia A using five-linked microsatellites.
Journal of thrombosis and haemostasis : JTH - 1 Mar 2006
Harraway J R, Smith M P, George P M
Abstract excerpt
BACKGROUND: Hemophilia A is a severe bleeding disorder caused by almost 1000 different known mutations in the F8C gene. Direct mutation analysis is sometimes difficult for this disorder. When a mutation cannot be found, linkage analysis can be used for prenatal and carrier diagnosis. AIM: To develop a rapid and effective system for carrier detection and prenatal diagnosis of hemophilia A based on a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.