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Dissecting PON1 Genotype Combinations Modulating Paraoxonase Activity and Risk of Dysglycemia and Liver Fibrosis

2026-04-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background & Aims</h4> Metabolic disorders such as dyslipidemia, metabolic dysfunction–associated steatotic liver disease (MASLD), and diabetes are promoted by chronic pro-inflammatory and pro-oxidative states. Paraoxonase 1 (PON1), a liver-derived HDL-associated enzyme, plays an important antioxidant role by hydrolyzing oxidized lipids and protecting against oxidative stress– induced damag...

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Literature Corpus work
6996e518-97cb-5619-b7f5-0ce0629e717f
DOI
10.64898/2026.04.09.26350501
Open publication

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Dissecting PON1 Genotype Combinations Modulating Paraoxonase Activity and Risk of Dysglycemia and Liver FibrosisDOI 10.64898/2026.04.09.26350501
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