Article
The PON1192RR genotype is associated with a higher prevalence of arterial hypertension.
Journal of hypertension - 1 Jul 2006
Marra Maurizio, Marchegiani Francesca, Antonicelli Roberto, Sirolla Cristina, Spazzafumo Liana, Olivieri Fabiola, Franceschi Claudio, Testa Roberto, Paolisso Giuseppe, James Richard W, Boemi Massimo, Parati Gianfranco
Abstract excerpt
OBJECTIVE: To investigate whether genetic polymorphism of paraoxonase (PON1192), an enzyme which protects low density lipoprotein from oxidation, is related to the prevalence of arterial hypertension. METHODS: Two groups of carefully selected subjects of both sexes were enrolled and compared. The first group comprised 219 healthy controls (mean age 46.5 +/- 14.7 years) whereas the second comprised 119...
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