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Article

R-carrying genotypes of serum paraoxonase (PON1) 192 polymorphism and higher activity ratio are related to susceptibility against ischemic stroke.

Molecular biology reports - 1 Dec 2012

Mahrooz Abdolkarim, Gohari Ghorban, Hashemi Mohammad-Bagher, Zargari Mehryar, Musavi Hadis, Abedini Mahmoud, Alizadeh Ahad

Abstract excerpt

The polymorphic gene of serum paraoxonase (PON1) and its activity involved in atherosclerosis. The purpose of the study was to analyze PON1 192 Q/R polymorphism and the enzyme activities in ischemic stroke. The polymorphism as the most common polymorphism in PON1 gene coding sequence is associated with variation in the enzyme activity and vascular disease. The study included 85 stroke patients and 71 control...

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Source

Identifiers

PMID: 23054002
DOI: 10.1007/s11033-012-2027-8

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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