Article
The rs243866/243865 polymorphisms in MMP-2 gene and the relationship with BP control in obese resistant hypertensive subjects.
Gene - 10 Mar 2018
Ritter Alessandra M V, de Faria Ana Paula, Barbaro Natália R, Sabbatini Andréa R, Corrêa Nathália Batista, Brunelli Veridiana, Fattori Andre, Amorim Rivadavio, Modolo Rodrigo, Moreno Heitor
Abstract excerpt
We sought to investigate whether the polymorphisms rs243865 (-1306C>T); rs243866 (-1575G>A) and rs2285053 (-735C>T) in metalloproteinases 2 - MMP-2 gene and rs17576 (Q279R), rs17577 (Q668R) and rs3918242 (-1562C>T) in MMP-9 gene are associated with clinical outcomes in obese resistant hypertensive (RH) subjects. One hundred and twenty RH were enrolled in this cross-sectional study and divided into obese (n=63)...