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Article

Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis.

DNA and cell biology - 1 Jun 2006

Trapasso Francesco, Drusco Alessandra, Costinean Stefan, Alder Hansjuerg, Aqeilan Rami I, Iuliano Rodolfo, Gaudio Eugenio, Raso Cinzia, Zanesi Nicola, Croce Carlo M, Fusco Alfredo

Abstract excerpt

Ptprj is a ubiquitously expressed murine gene encoding a receptor-type protein tyrosine phosphatase, which has recently been proposed as a candidate gene on the locus Scc1 for colon cancer susceptibility. It has been demonstrated that PTPRJ, the human homologue of Ptprj, is involved in the control of cell growth and adhesion, being furthermore altered in several types of cancer including mammary, thyroid, lung,...

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Source

Identifiers

PMID: 16792508
DOI: 10.1089/dna.2006.25.376

Genes

PTPRJ

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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