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Article

Mesothelin Is Not Required for Normal Mouse Development or Reproduction

1 Apr 2000

Abstract excerpt

Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function(s) of the protein is not known. We have analyzed the expression of the mouse mesothelin gene in different developmental stages and in various adult tissues by Northern hybridization. The 2.5-kb mesothelin transcript was detected in the mRNA of E...

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PMID: 10733593
DOI: 10.1128/mcb.20.8.2902-2906.2000

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