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Article

Characterization of mice deficient in the Src family nonreceptor tyrosine kinase Frk/rak.

Molecular and cellular biology - 1 Jul 2002

Chandrasekharan Subhashini, Qiu Ting Hu, Alkharouf Nawal, Brantley Kelly, Mitchell James B, Liu Edison T

Abstract excerpt

Frk/rak belongs to a novel family of Src kinases with epithelial tissue-specific expression. Although developmental expression patterns and functional overexpression in vitro have associated these kinases with growth suppression and differentiation, their physiological functions remain largely unknown. We therefore generated mice carrying a null mutation in iyk, the mouse homolog of Frk/rak. We report here that...

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Identifiers

PMID: 12077350
DOI: 10.1128/MCB.22.14.5235-5247.2002
PMCID: PMC139782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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