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Article

Phi-analysis at the experimental limits: mechanism of beta-hairpin formation.

Journal of molecular biology - 21 Jul 2006

Petrovich Miriana, Jonsson Amanda L, Ferguson Neil, Daggett Valerie, Fersht Alan R

Abstract excerpt

The 37-residue Formin-binding protein, FBP28, is a canonical three-stranded beta-sheet WW domain. Because of its small size, it is so insensitive to chemical denaturation that it is barely possible to determine accurately a denaturation curve, as the transition spans 0-7 M guanidinium hydrochloride (GdmCl). It is also only marginally stable, with a free energy of denaturation of just 2.3 kcal/mol at 10 degrees...

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Source

Identifiers

PMID: 16784750
DOI: 10.1016/j.jmb.2006.05.050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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