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Article

Characterization of a strain-specific CD-1 reference genome reveals potential inter- and intra-strain functional variability.

BMC genomics - 3 Aug 2023

Jung Yoon Hee, Wang Hsiao-Lin V, Ali Samir, Corces Victor G, Kremsky Isaac

Abstract excerpt

BACKGROUND: CD-1 is an outbred mouse stock that is frequently used in toxicology, pharmacology, and fundamental biomedical research. Although inbred strains are typically better suited for such studies due to minimal genetic variability, outbred stocks confer practical advantages over inbred strains, such as improved breeding performance and low cost. Knowledge of the full genetic variability of CD-1 would make...

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PMID: 37537522
DOI: 10.1186/s12864-023-09523-x
PMCID: PMC10401811

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