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Article

Efficient T cell activation via a Toll-Interleukin 1 Receptor-independent pathway.

Immunity - 1 Jun 2006

Janssen Edith, Tabeta Koichi, Barnes Michael J, Rutschmann Sophie, McBride Sara, Bahjat Keith S, Schoenberger Stephen P, Theofilopoulos Argyrios N, Beutler Bruce, Hoebe Kasper

Abstract excerpt

Here, we describe a previously unrecognized pathway for activation of antigen-specific adaptive immune responses that was independent of Toll-Interleukin 1 Receptor signaling and directed toward detection of antigens expressed by apoptotic cells. This pathway is represented within Flt-3 Ligand-derived dendritic cells (DCs) that represent immature lymphoid DCs, but not within GM-CSF-treated bone marrow-derived...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16782034
DOI: 10.1016/j.immuni.2006.03.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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