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Article

Apoptosis-mediated enhancement of DNA-raised immune responses by mutant caspases.

Nature biotechnology - 1 Jun 2001

Sasaki S, Amara R R, Oran A E, Smith J M, Robinson H L

Abstract excerpt

Apoptotic bodies can be used to target delivery of DNA-expressed immunogens into professional antigen-presenting cells (APCs). Here we show that antigen-laden apoptotic bodies created by vectors co-expressing influenza virus hemagglutinin (HA) or nucleoprotein (NP) genes and mutant caspase genes...

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Identifiers

PMID: 11385458
DOI: 10.1038/89289

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11385458-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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