A model-based approach to selection of tag SNPs.

doi:10.1186/1471-2105-7-303

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Article

A model-based approach to selection of tag SNPs.

BMC bioinformatics - 15 Jun 2006

Nicolas Pierre, Sun Fengzhu, Li Lei M

Abstract excerpt

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identification of sets of tag SNPs that capture as much haplotype information as possible. Tag SNP selection is analogous to th...

Topics

Databases, Genetic
Genetic Markers
Haplotypes
Humans
Linkage Disequilibrium
Markov Chains
Models, Genetic
Polymorphism, Single Nucleotide
Reproducibility of Results
Sequence Analysis, DNA
Software

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