Article
Informative SNP selection methods based on SNP prediction.
IEEE transactions on nanobioscience - 1 Mar 2007
He Jingwu, Zelikovsky Alexander
Abstract excerpt
The search for the association between complex diseases and single nucleotide polymorphisms (SNPs) or haplotypes has recently received great attention. For these studies, it is essential to use a small subset of informative SNPs, i.e., tag SNPs, accurately representing the rest of the SNPs. Tag SNP selection can achieve: 1) considerable budget savings by genotyping only a limited number of SNPs and...
Topics
- Algorithms
- Artificial Intelligence
- Base Sequence
- Computer Simulation
- DNA Mutational Analysis
- Expressed Sequence Tags
- Genotype
- Haplotypes
- Linkage Disequilibrium
- Models, Genetic
- Models, Statistical