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Article

A model-based approach to capture genetic variation for future association studies.

Genome research - 1 Jan 2007

Eyheramendy Susana, Marchini Jonathan, McVean Gilean, Myers Simon, Donnelly Peter

Abstract excerpt

Genome-wide association studies are still constrained by the cost of genotyping. For this reason, the selection of a reduced set of markers or tags able to capture a significant proportion of the genetic variation is an important aspect of these studies. Most tagging SNP selection methods have been successful in capturing the genetic variation of the data from which the tags have been chosen. However, when these...

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PMID: 17095708
DOI: 10.1101/gr.5675406
PMCID: PMC1716272

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