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Article

Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer.

British journal of cancer - 6 Nov 2012

Pal T, Akbari M R, Sun P, Lee J-H, Fulp J, Thompson Z, Coppola D, Nicosia S, Sellers T A, McLaughlin J, Risch H A, Rosen B, Shaw P, Schildkraut J, Narod S A

Abstract excerpt

BACKGROUND: Mutations in genes for hereditary non-polyposis colorectal cancer (HNPCC) in ovarian cancer patients remains poorly defined. We sought to estimate the frequency and characteristics of HNPCC gene mutations in a population-based sample of women with epithelial ovarian cancer. METHODS: The analysis included 1893 women with epithelial ovarian cancer ascertained from three population-based studies....

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to Carcinoma, Ovarian Epithelial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Share to DNA Mismatch Repair

Share to MutL Protein Homolog 1

Share to MutS Homolog 2 Protein

Share to Neoplasms, Glandular and Epithelial

Share to Ovarian Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 23047549
DOI: 10.1038/bjc.2012.452
PMCID: PMC3493867

Genes

MSH6
MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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