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Article

Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans.

The FEBS journal - 1 Jul 2006

Zameitat Elke, Gojković Zoran, Knecht Wolfgang, Piskur Jure, Löffler Monika

Abstract excerpt

Candida albicans is the most prevalent yeast pathogen in humans, and recently it has become increasingly resistant to the current antifungal agents. In this study we investigated C. albicans dihydroorotate dehydrogenase (DHODH, EC 1.3.99.11), which catalyzes the fourth step of de novo pyrimidine synthesis, as a new target for controlling infection. We propose that the enzyme is a member of the DHODH family 2,...

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Source

Identifiers

PMID: 16774642
DOI: 10.1111/j.1742-4658.2006.05327.x

Genes

DHODH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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