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Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer

20 Apr 2020

Abstract excerpt

Dehydrogenases are oxidoreductase enzymes that play a variety of fundamental functions in the living organisms and have primary roles in pathogen survival and infection processes as well as in cancer development. We review here a sub-set of NAD-dependent dehydrogenases involved in human diseases and the recent advancements in drug development targeting pathogen-associated NAD-dependent dehydrogenases. We focus...

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PMID: 32311017
DOI: 10.1042/bst20191261

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