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Article

Organ and cell specificity of base excision repair mutants in mice.

Mutation research - 3 Jan 2007

Larsen Elisabeth, Meza Trine J, Kleppa Liv, Klungland Arne

Abstract excerpt

Genetically modified mouse models are a powerful approach to study the relation of a single gene-deletion to processes such as mutagenesis and carcinogenesis. The generation of base excision repair (BER) deficient mouse models has resulted in a re-examination of the cellular defence mechanisms that exist to counteract DNA base damage. This review discusses novel insights into the relation between specific...

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Identifiers

PMID: 16765995
DOI: 10.1016/j.mrfmmm.2006.01.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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