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Article

Genome instability and DNA damage accumulation in gene-targeted mice.

Neuroscience - 14 Apr 2007

Nordstrand L M, Ringvoll J, Larsen E, Klungland A

Abstract excerpt

Six major pathways for DNA repair have been identified. These include (1) DNA repair by direct reversal, (2) base excision repair, (3) mismatch repair, (4) nucleotide excision repair, (5) homologous recombination, and (6) non-homologous end-joining. In addition, several other cellular processes influence the response to DNA damage. The generation of gene-targeted organisms is crucial for assessing the relative...

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Identifiers

PMID: 17218062
DOI: 10.1016/j.neuroscience.2006.10.059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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