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Article

Mutations induced by carcinogenic doses of aristolochic acid in kidney of Big Blue transgenic rats.

Toxicology letters - 10 Sept 2006

Chen Ling, Mei Nan, Yao Lei, Chen Tao

Abstract excerpt

Aristolochic acid (AA) is present in at least 65 different kinds of plants, many of which are used as herbal folk remedies. AA is considered one of the most potent plant carcinogens in humans and animals. It has been associated with the development of urothelial cancers in humans, and kidney and forestomach tumors in rats. In the present study, we used the Big Blue transgenic rat model to evaluate the...

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Identifiers

PMID: 16764999
DOI: 10.1016/j.toxlet.2006.04.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations induced by carcinogenic doses of aristolochic acid in kidney of Big Blue transgenic rats.PMID 16764999Read ↗

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