Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and epigenetic characteristics of gastric cancers with JC virus T-antigen.

World journal of gastroenterology - 28 Nov 2009

Yamaoka Satoshi, Yamamoto Hiroyuki, Nosho Katsuhiko, Taniguchi Hiroaki, Adachi Yasushi, Sasaki Shigeru, Arimura Yoshiaki, Imai Kohzoh, Shinomura Yasuhisa

Abstract excerpt

AIM: To clarify the significance of JC virus (JCV) T-antigen (T-Ag) expression in human gastric cancer. METHODS: We investigated the relationship between T-Ag detected by immunohistochemistry and Epstein-Barr virus (EBV) infection, microsatellite instability (MSI), and genetic and epigenetic alterations in gastric cancers. Mutations in the p53, beta-catenin, KRAS, BRAF, PIK3CA genes were analyzed by polymerase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Antigens, Viral, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Immunohistochemistry

Share to JC Virus

Share to Loss of Heterozygosity

Share to Microsatellite Repeats

Share to Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 19938198
DOI: 10.3748/wjg.15.5579
PMCID: PMC2785062

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and epigenetic characteristics of gastric cancers with JC virus T-antigen.PMID 19938198Read ↗

Oncogenic T‐antigen of JC virus is present frequently in human gastric cancersSemantic proximity Read ↗

High JC virus load in gastric cancer and adjacent non‐cancerous mucosaSemantic proximity Read ↗

DNA Methylation and Genetic Aberrations in Gastric CancerSemantic proximity Read ↗

Epigenetics and DNA Base Substitutions of Epstein-Barr Virus (EBV)-Related Gastric Cancers: Implications for Targeted Therapies.Semantic proximity Read ↗

Molecular pathology of gastric carcinoma.Semantic proximity Read ↗

Association of JC virus T-antigen expression with the methylator phenotype in sporadic colorectal cancers.Semantic proximity Read ↗

Epigenetic dysregulation in Epstein-Barr virus-associated gastric carcinoma: Disease and treatmentsSemantic proximity Read ↗

Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus.Semantic proximity Read ↗

JC Virus T-Antigen in Colorectal Cancer Is Associated with p53 Expression and Chromosomal Instability, Independent of CpG Island Methylator PhenotypeSemantic proximity Read ↗

Prognostic implication of molecular subtypes and response to neoadjuvant chemotherapy in 760 gastric carcinomas: role of Epstein–Barr virus infection and high‐ and low‐microsatellite instabilitySemantic proximity Read ↗

Epigenetic Regulation of Tumor Suppressors by<i>Helicobacter pylori</i>Enhances EBV-Induced Proliferation of Gastric Epithelial CellsSemantic proximity Read ↗

Genome-Wide DNA Methylation Profiles in Noncancerous Gastric Mucosae with Regard to Helicobacter pylori Infection and the Presence of Gastric CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.