Article
No association of eight TNFAIP3 single nucleotide variants to rheumatoid arthritis in Mexicans.
Molecular biology reports - 1 Nov 2022
Aranda-Uribe Ivan Sammir, Ramírez-Bello Julian, Victoria-Acosta Georgina, Muñoz-González Felipe, Barbosa-Cobos Rosa Elda, Moreno José
Abstract excerpt
Rheumatoid arthritis (RA) is a chronic inflammatory disease of autoimmune origin with many associated genetic traits, including genes related to the control of inflammation. The A20 protein, encoded by the TNFAIP3 gene, is a negative regulator of NF-kB mediated inflammation. Several single nucleotide variants (SNVs) of TNFAIP3 are associated with susceptibility to RA in different ethnic groups, none of which has...
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