Article
Relationship between SNPs and expression level for candidate genes in rheumatoid arthritis.
Scandinavian journal of rheumatology - 1 Jan 2015
Fodil M, Teixeira V H, Chaudru V, Hilliquin P, Bombardieri S, Balsa A, Westhovens R, Barrera P, Alves H, Migliorin P, Bardin T, Cornelis F, Boudjema A, Petit-Teixeira E
Abstract excerpt
OBJECTIVES: The study of polymorphisms of genes differentially expressed may lead to the identification of putative causal genetic variants in multifactorial diseases such as rheumatoid arthritis (RA). Based on preceding transcriptomic results, we genotyped 10 single nucleotide polymorphisms (SNPs) belonging to six genes (S100A8, RNASE2, PGLYRP1, RUNX3, IL2RB, and LY96) showing the highest fold change (> 1.9)...
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