The type 1 diabetes susceptibility gene SUMO4 at IDDM5 is not associated with susceptibility to rheumatoid arthritis or juvenile idiopathic arthritis.

doi:10.1093/rheumatology/kei041

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The type 1 diabetes susceptibility gene SUMO4 at IDDM5 is not associated with susceptibility to rheumatoid arthritis or juvenile idiopathic arthritis.

Rheumatology (Oxford, England) - 1 Nov 2005

Gibbons L J, Thomson W, Zeggini E, Worthington J, Barton A, Eyre S, Donn R, Hinks A

Abstract excerpt

OBJECTIVES: Linkage and association of rheumatoid arthritis (RA) and rheumatoid factor (RF)-negative juvenile idiopathic arthritis (JIA) has previously been demonstrated to the type 1 diabetes (T1D) locus, IDDM5, on chromosome 6q25. An association of a methionine-to-valine polymorphism (rs237025, 163A --> G, M55V) in the SUMO4 gene within IDDM5 has recently been described in T1D. The objective of this study was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Arthritis, Juvenile

Share to Arthritis, Rheumatoid

Share to Autoimmune Diseases

Share to Case-Control Studies

Share to Diabetes Mellitus, Type 1

Share to Gene Frequency

Share to Small Ubiquitin-Related Modifier Proteins

Source

Open in PubMed

Identifiers

PMID: 16159953
DOI: 10.1093/rheumatology/kei041

Genes

SUMO4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The type 1 diabetes susceptibility gene SUMO4 at IDDM5 is not associated with susceptibility to rheumatoid arthritis or juvenile idiopathic arthritis.PMID 16159953Read ↗

SLC22A4, RUNX1, and SUMO4 polymorphisms are not associated with rheumatoid arthritis: a case-control study in a Spanish population.Semantic proximity Read ↗

Fine mapping of genes within the IDDM8 region in rheumatoid arthritis.Semantic proximity Read ↗

Exploration of shared genetic susceptibility loci between type 1 diabetes and rheumatoid arthritis in the Pakistani populationSemantic proximity Read ↗

Association of SUMO4 M55V polymorphism with autoimmune diabetes in Latvian patients.Semantic proximity Read ↗

Evidence for the role of small ubiquitin-like modifier 4 as a general autoimmunity locus in the Japanese population.Semantic proximity Read ↗

The IDDM13 region containing the insulin-like growth factor binding protein-5 (IGFBP5) gene on chromosome 2q33-q36 and the genetic susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

Genetic and functional evidence supporting SUMO4 as a type 1 diabetes susceptibility gene.Semantic proximity Read ↗

Association of small ubiquitin-like modifier 4 (SUMO4) variant, located in IDDM5 locus, with type 2 diabetes in the Japanese population.Semantic proximity Read ↗

PADI4 (rs2240340), PDCD1 (rs10204525), and CTLA4 (231775) gene polymorphisms and polyarticular juvenile idiopathic arthritis.Semantic proximity Read ↗

Case-control Association Study of Autoimmunity Associated Variants in PDCD1 and Juvenile Idiopathic Arthritis.Semantic proximity Read ↗

SUMO4 and MAP3K7IP2 single nucleotide polymorphisms and susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

SUMO4 and its role in type 1 diabetes pathogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.