Article
Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes.
International journal of obesity (2005) - 1 Feb 2007
Larsen L H, Rose C S, Sparsø T, Overgaard J, Torekov S S, Grarup N, Jensen D P, Albrechtsen A, Andersen G, Ek J, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O
Abstract excerpt
BACKGROUND: The estrogen-related receptor alpha (ERRalpha or NR3B1) is a transcription factor from the nuclear receptor super-family, group III. The gene encoding ERRalpha (ESRRA) is located on chromosome 11q13, a region showing genetic linkage to body mass index and fat percentage. Through inter...
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