Article
REV-ERB ALPHA polymorphism is associated with obesity in the Spanish obese male population.
PloS one - 1 Jan 2014
Ruano Elena G, Canivell Silvia, Vieira Elaine
Abstract excerpt
REV-ERB ALPHA has been shown to link metabolism with circadian rhythms. We aimed to identify new polymorphisms in the promoter of REV-ERB ALPHA and tested whether these polymorphisms could be associated with obesity in the Spanish population. Of the 1197 subjects included in our study, 779 were obese (BMI 34.38±3.1 kg/m2) and 418 lean (BMI 23.27±1.5 kg/m2). In the obese group, 469 of the 779 had type 2 diabetes....
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