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Article

Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis--a cohort study.

BMC medical genetics - 4 Dec 2007

Nilsson Maria, Dahlman Ingrid, Jiao Hong, Gustafsson Jan-Ake, Arner Peter, Dahlman-Wright Karin

Abstract excerpt

BACKGROUND: The estrogen receptors alpha and beta (ESR1, ESR2) have been implicated in adiposity, lipid metabolism and feeding behaviour. In this report we analyse ESR1 and ESR2 gene single nucleotide polymorphisms (SNPs) for association with obesity. We also relate adipose tissue ESR1 mRNA levels and ESR1 SNPs to adipocyte lipolysis and lipogenesis phenotypes. METHODS: 23 ESR1 and 11 ESR2 tag-SNPs, covering most...

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Source

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Identifiers

PMID: 18053221
DOI: 10.1186/1471-2350-8-73
PMCID: PMC2238734

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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