Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study.

doi:10.2337/db06-1017

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Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study.

Diabetes - 1 Aug 2007

Gallagher Carla J, Langefeld Carl D, Gordon Candace J, Campbell Joel K, Mychaleckyj Josyf C, Mychalecky Josyf C, Bryer-Ash Michael, Rich Stephen S, Bowden Donald W, Sale Michèle M

Abstract excerpt

OBJECTIVE: We previously detected an association between a region of the estrogen receptor-alpha (ESR1) gene and type 2 diabetes in an African-American case-control study; thus, we investigated this region for associations with the metabolic syndrome and its component traits in African-American families from the Insulin Resistance Atherosclerosis Family Study. RESEARCH DESIGN AND METHODS: A total of 17 single...

Topics

Adiposity
Adult
Black or African American
Atherosclerosis
Diabetes Mellitus, Type 2
Estrogen Receptor alpha
Female
Glucose
Homeostasis
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin Resistance

Introns

Lipid Metabolism

Male

Metabolic Syndrome

Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 17513703
DOI: 10.2337/db06-1017

Genes

ESR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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